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Orphan gene
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Orphan gene : ウィキペディア英語版
Orphan gene
Orphan genes (also called ORFans, especially in microbial literature) are genes without homologues in other lineages.〔 Orphans are a subset of taxonomically-restricted genes (TRGs), which are unique to a specific taxonomic level (e.g. plant-specific).〔 In contrast to non-orphan TRGs, orphans are usually considered unique to a very narrow taxon, generally a species.
The classic model of evolution is based on duplication, rearrangement, and mutation of genes with the idea of common descent. Orphan genes differ in that they are lineage-specific with no known history of shared duplication and rearrangement outside of their specific species or clade. Orphan genes may arise through a variety of mechanisms, such as horizontal gene transfer, duplication and rapid divergence, and de novo origination,〔 and may act at different rates in insects, primates, and plants. Despite their relatively recent origin, orphan genes may encode functionally important proteins.
==Definition==
In order to be considered an orphan gene, the gene must be encoding a protein that lacks homology to any predicted peptide from other genomes of similar species.〔 Orphans are a subset of taxonomically-restricted genes (TRGs), which are unique to a specific taxonomic level (e.g. plant-specific).〔 In contrast, orphans are usually considered unique to a very narrow taxon, generally a species.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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